10 Best Audio Interfaces With MIDI Ports in 2026 for Home Studios and Live Setups

The best audio interface with MIDI ports can simplify a home studio by combining quality recording, instrument control, and reliable computer connectivity in one device.

These 10 options cover different needs, including podcasting, music production, hardware synthesizers, MIDI keyboards, and multi-input recording. The right choice depends on your I/O requirements, workflow, and budget.

Best 10 Audio Interface with Midi Ports Picks for 2026

Best Value 4×4 – U-PHORIA UMC404HD

The Behringer U-PHORIA UMC404HD is a practical audio interface with MIDI ports for recording several microphones or instruments at once. It combines four MIDAS-designed mic preamps, 24-bit/192 kHz operation, and 4-in/4-out connectivity in a durable metal chassis.

Best For: Home studios that need four analog inputs, phantom power, and basic MIDI connectivity at a value-oriented price.

Pros:

• Four mic preamps with +48V phantom power
• 24-bit/192 kHz recording resolution
• Includes one MIDI input/output and four outputs
• Impact-resistant metal chassis

Cons:

• Uses USB 2.0 rather than USB-C
• Its MIDI I/O is limited to one input and one output

Choose the UMC404HD if you want a straightforward, multi-input interface with MIDI for computer-based recording. Its four preamps and sturdy construction make it especially useful for small recording setups.

Best All-Rounder – Scarlett 4i4 4th Gen

The Focusrite Scarlett 4i4 4th Gen is a versatile audio interface with MIDI ports for connecting microphones, guitars, synths, drum machines, and other studio gear. Its USB-C connection, 4-in/4-out design, Auto Gain, Clip Safe, and Air modes make it a flexible choice for modern recording workflows.

Best For: Producers and home-recording musicians who want broad connectivity, easy level management, and included recording software.

Pros:

• Two mic preamps, two Hi-Z inputs, four line inputs, and four outputs
• Includes MIDI input/output and USB-C connectivity
• 120 dB dynamic range with 24-bit/192 kHz operation
• Auto Gain, Clip Safe, and Air modes simplify recording

Cons:

• Only two of the inputs are mic preamps
• Some advanced features may be unnecessary for simpler setups

The Scarlett 4i4 is a strong general-purpose pick when you need an audio interface with MIDI ports and room for line-level studio equipment. Its software bundle and recording-assistance features add useful value for new and experienced producers alike.

Best MIDI Adapter – FORE T1 USB-C MIDI Interface

The FORE T1 is a compact MIDI-to-USB-C interface for connecting a keyboard, synthesizer, electronic drum kit, or other five-pin MIDI device to a computer or mobile device. It is a MIDI adapter rather than a microphone recording interface, making it useful when your main goal is reliable MIDI data transfer.

Best For: Musicians who need a simple USB-C connection between traditional five-pin MIDI hardware and compatible phones, tablets, Macs, or Windows computers.

Pros:

• Provides one MIDI input and one MIDI output across 16 channels
• Plug-and-play design with built-in driver
• LED indicators show power and signal activity
• Works with listed software including GarageBand, FL Studio, and Cubase

Cons:

• Does not provide microphone or instrument audio inputs
• USB A-C adapter is not included
• Requires devices with five-pin DIN MIDI ports

If you already have an audio interface and only need MIDI connectivity, the FORE T1 offers a focused, portable solution. Be sure your equipment uses standard five-pin DIN MIDI and that you have the appropriate adapter for your device.

Best for DSP Workflows – Zen Quadro Synergy Core

The Antelope Audio Zen Quadro is a feature-rich audio interface with MIDI ports for creators who need advanced routing, multiple connections, and real-time processing. It offers four discrete preamps, dual USB-C, expandable digital connectivity, and Synergy Core effects running on dedicated DSP and FPGA hardware.

Best For: Mobile producers, streamers, and small studios that need flexible routing, low-latency effects, and extensive expansion options.

Pros:

• Four discrete mic preamps with up to 75 dB of gain
• 37 included real-time effects with additional options available
• Dual USB-C supports computer-plus-mobile or two-computer workflows
• 14-in/10-out expansion with ADAT and S/PDIF connectivity

Cons:

• More features than needed for a basic recording setup
• Its advanced routing and effects may require additional setup time

The Zen Quadro suits users who want an audio interface with MIDI ports that can also act as a central hub for streaming, mobile production, and expandable studio systems. Its dedicated processing and dual USB-C design are the main reasons to choose it over a simpler interface.

Best MIDI Router – CME H4MIDI WC

The CME H4MIDI WC is a specialized choice for musicians who need an audio interface with MIDI ports and advanced routing rather than traditional microphone recording. It connects USB MIDI instruments directly to MIDI hardware, works with computers and mobile devices, and can run standalone from USB or 9V power.

Best For: Guitarists, producers, and performers building compact MIDI pedalboard or hardware setups.

Pros:

• Supports up to 2-in/2-out 5-pin DIN MIDI and up to eight USB MIDI devices through a hub.
• Offers MIDI thru, split, merge, mapping, and filtering through HxMIDI Tools.
• Works with macOS, Windows, iOS, Android, Linux, and ChromeOS.
• Compact design, four onboard presets, and standalone 5V USB or 9V DC power support mobile use.

Cons:

• It is focused on MIDI connectivity and does not provide conventional microphone or line-level audio inputs.
• WIDI Bluetooth MIDI requires the optional WIDI Core module.

The H4MIDI WC is best understood as a flexible MIDI host and router, not a standard recording interface. Choose it when hardware MIDI control, USB host support, and portable routing are more important than recording audio.

Best Beginner Recording Interface – Focusrite Scarlett 2i2 4th Gen

The Focusrite Scarlett 2i2 4th Gen is a strong recording-focused option for shoppers comparing an audio interface with MIDI ports, although this model does not list dedicated MIDI I/O. It provides two microphone or instrument inputs, high-resolution conversion, and automatic level-management tools for straightforward vocal and guitar recording.

Best For: Beginners and home recordists who need simple two-channel audio recording.

Pros:

• Two mic preamps and two Hi-Z instrument inputs support microphones, guitars, and other sources.
• Provides 24-bit/192kHz recording and a 120dB dynamic range.
• Auto Gain and Clip Safe help manage recording levels and reduce clipping.
• Includes Air mode plus a broad software bundle with Pro Tools Intro+, Ableton Live Lite, Cubase LE, and Hitmaker Expansion.

Cons:

• Dedicated MIDI ports are not listed in the supplied specifications.
• It has two audio channels, so larger recording setups will need additional inputs.

The Scarlett 2i2 is a practical pick when audio recording is the priority and MIDI can be handled separately. If built-in keyboard or synth MIDI connections are essential, consider a model with explicitly listed MIDI I/O instead.

Best Audio Interface With MIDI – Mackie Onyx Producer 2-2

The Mackie Onyx Producer 2-2 is a straightforward audio interface with MIDI ports for musicians who want recording inputs and hardware MIDI connectivity in one compact unit. It combines two Onyx mic preamps, combo inputs, 2-in/2-out recording, and MIDI I/O with bus-powered operation.

Best For: Home musicians recording vocals or instruments while connecting MIDI keyboards and other hardware.

Pros:

• Combines 2-in/2-out, 24-bit/192kHz recording with MIDI I/O.
• Two Onyx mic preamps include 48V phantom power for condenser microphones.
• XLR/TRS combo inputs accept mic, line, and Hi-Z instrument sources.
• Offers zero-latency direct monitoring, a headphone output, and bus-powered USB operation.

Cons:

• Only two audio inputs and two outputs are available for recording and monitoring.
• The supplied details list a one-year warranty.

The Onyx Producer 2-2 is the clearest fit here for buyers specifically seeking an audio interface with MIDI ports alongside basic recording capability. Its compact 2×2 layout suits smaller studios, mobile setups, and musicians who do not need numerous simultaneous inputs.

Premium Choice – Universal Audio Volt 2

The Universal Audio Volt 2 is a strong audio interface with MIDI ports for musicians, podcasters, and streamers who want two-channel recording with high-resolution sound. Its Vintage mode, 610 preamp emulation, and support for recording up to 24-bit/192 kHz add flexibility for polished home-studio work.

Best For: Musicians and creators who prioritize high-resolution recording, classic preamp character, and broad Mac, Windows, and mobile compatibility.

Pros:

• Two-channel USB-C interface with MIDI connectivity.
• Vintage mode provides 610-style tube preamp emulation.
• Supports recording and playback up to 24-bit/192 kHz.
• Includes access to LUNA and supports UAD plug-ins and instruments.

Cons:

• Mobile recording may require an external Volt power supply and Apple adapter, depending on the device.
• Its one-year warranty is relatively limited.

The Volt 2 stands out when sound quality and classic preamp flavor matter more than having a larger number of inputs. It is a capable compact hub for MIDI-equipped recording setups.

Best Value – PreSonus AudioBox 96

The PreSonus AudioBox 96 is a practical audio interface with MIDI ports for home recording and portable setups. It combines two Class-A mic preamps, instrument inputs, 24-bit/96 kHz conversion, and USB bus power in a straightforward two-channel design.

Best For: Beginners and mobile recordists who want MIDI I/O, phantom power, zero-latency monitoring, and a useful software bundle.

Pros:

• Includes MIDI input and output alongside two mic and instrument channels.
• USB bus-powered design does not require an additional power supply.
• Offers up to 24-bit/96 kHz recording and playback.
• Includes Studio One Artist, Ableton Live Lite, and the Studio Magic Plug-In suite after registration.

Cons:

• Maximum sample rate is lower than the Volt 2’s 192 kHz capability.
• The global 48V phantom-power control may offer less flexibility for mixed microphone setups.

With its bus-powered operation, MIDI I/O, and bundled software, the AudioBox 96 is an accessible choice for building a compact recording rig without adding a separate power supply.

Budget Pick – M-Audio M-Track Duo

The M-Audio M-Track Duo is a compact audio interface with MIDI ports suited to basic recording, podcasting, and live streaming setups. Its two combo inputs accept microphone, line, or instrument signals, while the USB/Direct switch supports zero-latency monitoring.

Best For: Budget-conscious creators who need a simple two-input interface for vocals, guitar, streaming, or podcast production.

Pros:

• Two combo XLR/line/instrument inputs with phantom power.
• USB/Direct monitoring switch helps reduce monitoring latency.
• Includes a headphone output and stereo main outputs.
• Comes with MPC Beats for production and recording.

Cons:

• Supports up to 48 kHz, below the sample rates offered by the other listed interfaces.
• The supplied notes do not list MIDI I/O among its connectivity specifications, so confirm port requirements before buying.

The M-Track Duo keeps the core recording controls simple and portable. It is a sensible entry-level option for two-channel recording, but shoppers specifically requiring physical MIDI ports should verify the exact configuration first.

How We Picked the Best Audio Interface with Midi Ports

We focused on interfaces and MIDI devices that support practical computer-based recording workflows while offering useful connectivity for keyboards, controllers, drum machines, or other MIDI hardware. We considered input and output counts, preamp quality, conversion specifications, USB connectivity, monitoring features, driver or software support, and overall flexibility.

Because these products are not identical, the list includes both full audio interfaces with built-in MIDI I/O and compact MIDI-focused devices. Check the specifications carefully if you need traditional 5-pin MIDI ports rather than USB MIDI, or if you require audio inputs and outputs in addition to MIDI control.

Quick Comparison

Best For	What to Look For
Solo recording	Two quality inputs, direct monitoring, and simple controls
Small bands or hardware-heavy setups	Four or more inputs, multiple outputs, and MIDI I/O
MIDI keyboards and controllers	Reliable USB MIDI or 5-pin MIDI connectivity
Portable production	Bus power, compact construction, and USB-C compatibility
Mixing and live routing	Independent outputs, low-latency monitoring, and loopback or software mixing

Key Buying Factors for an Audio Interface with Midi Ports

Audio I/O and Preamps

Start with the number of microphones, instruments, or line-level devices you plan to record at once. Two inputs suit most solo musicians, while four-input models provide more room for stereo instruments, hardware, or small ensembles. Look for phantom power if you use condenser microphones and high-impedance instrument inputs for guitar or bass.

MIDI Connectivity

Confirm whether the unit includes 5-pin MIDI input and output, USB MIDI, or both. Traditional MIDI is useful for synthesizers and older keyboards; USB MIDI is convenient for modern controllers and computer-based setups. Some compact MIDI interfaces are not audio interfaces, so verify that they meet your recording needs.

Latency, Monitoring, and Compatibility

Direct monitoring can help you hear live inputs without distracting delay. Also check operating-system support, USB-C or USB-A requirements, bus-power behavior, and whether the included software fits your workflow. Extra outputs matter if you plan to connect studio monitors, headphones, external effects, or a mixer.

Who Should Buy Which Audio Interface with Midi Ports?

Choose a two-channel model if you mainly record vocals, guitar, or a single stereo source. A four-channel interface is better for musicians who use several instruments or want to integrate external MIDI hardware and multiple line connections. If MIDI control is your priority and you already own an audio interface, a dedicated MIDI host or USB MIDI interface may be the more efficient purchase.

For beginners, prioritize straightforward controls, dependable drivers, and the connections you need today. More advanced producers should consider expandable I/O, independent outputs, software routing, and the ability to connect several hardware instruments. Before buying, map your complete setup—including microphones, monitors, headphones, MIDI devices, and future upgrades—so the interface remains useful as your studio grows.